FindTrial
Sign In

Comparison of postoperative analgesic effects of serratus anterior plane block alone and combined with anterior cutaneous branches block of intercostal nerve in rhinoplasty with autogenous costal cartilage

Comparison of postoperative analgesic effects of serratus anterior plane block alone and combined with anterior cutaneous branches block of intercostal nerve in rhinoplasty with autogenous costal cartilage

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057430
Enrollment
Unknown
Registered
2022-03-12
Start date
2022-03-07
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with autogenous costal cartilage rhinoplasty

Interventions

A:Serratus anterior plane block(ropivacaine)+PCIA
B:Serratus anterior plane block (Ropivacaine + compound betamethasone) +PCIA
C:serratus anterior plane block combined with anterior cutaneous branches block of intercostal nerve(Ropivacaine + compound betamethasone)+PCIA

Sponsors

Plastic Surgery Hospital, CAMS, PUMC
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients receiving general anesthesia for primary augmentation rhinoplasty with autologous costal cartilage; 2. Age = 18 and = 60, regardless of gender; 3. The American Association of Anesthesiologists (ASA) is classified as I-II; 4. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Past chronic pain (lasting for at least 3 months) or long-term history of taking analgesics (such as opioids, acetaminophen or NSAIDs); 2. History of abnormal blood coagulation; 3. Immune diseases, having taken immunosuppressive drugs (such as hormones, anti-inflammatory drugs, etc.) within 3 months; 4. Allergies to the drugs to be used; 5. History of diabetes; 6. Skin infection at puncture site of nerve block; 7. People with language mental disorder and unable to complete the numerical rating scale (NRS) of pain.

Design outcomes

Primary

MeasureTime frame
resting,coughing NRS;—

Secondary

MeasureTime frame
Intraoperative dosage of sufentanil and remifentanil;Dosage of sufentanil analgesic pump within 24 hours after surgery;The time of the first oral analgesic, the number and total dose of oral analgesic after operation;Duration of postoperative analgesia;Intraoperative blood pressure, heart rate, SPO2,BIS,PETCO2;Ramsay score;Opioid side effects(nausea and vomiting?Dizziness?pruritus?sleepiness?respiratory depression,etc);first time out of bed;the satisfaction of patients;—

Countries

CHINA

Contacts

Public ContactChunmei Chen

Plastic Surgery Hospital, Chinese Academy of Medical Sciences

chunmeichen2008@163.com+86 18611612186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026