emergence agitation
Conditions
Interventions
Remifentanil treatment group:Remifentanil treatment
Propofol treatment group:Propofol treatment
Sponsors
The First Affiliated Hospital of USTC
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with restlessness in the resuscitation room after elective general anesthesia; 2. 18 = 65; 3. 18 kg/m2 < body mass index (BMI) < 30 kg/m2; 4. American Society of Anesthesiologists (ASA) Grade I~III.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot communicate normally before operation; 2. Patients with mental illness; 3. Grade II and above atrioventricular block, bradycardia (HR<50 points/time), hypotension (NBP<90/60mmHg); 4. Patients with hypertension and poor blood pressure control (systolic blood pressure = 160mmHg or diastolic blood pressure = 110mmHg); 5. Patients with a history of opiate allergy or addiction; 6. Patients allergic to propofol; 7. Patients who are given muscle relaxants within 30 minutes after
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A recurrent emergence agitation within 15 min after intervention.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Riker sedation-agitation (RSAS) score after treatment at different time points.;Patient's vital signs (blood pressure, heart rate, blood oxygen saturation) at different time points;Coughing response during emergence;Time to remove the tracheal tube;Proportion of patients with PONV;Numerical Rating Scale (NRS) and rescue medication;Adverse events in the PACU;Time to discharge from the PACU; | — |
Countries
China
Contacts
Public ContactWang Sheng
The First Affiliated Hospital of USTC
Outcome results
None listed