Efficacy and safety of radical prostatectomy immediately after the diagnosis of prostate cancer by frozen section during prostate targeted biopsy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200057402

Enrollment

Unknown

Registered

2022-03-11

Start date

2022-03-12

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prostate cancer

Interventions

Test group:Intraoperative frozen section

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1.=80 years old, ECOG PS =1 , no obvious contraindication for surgery; 2.Patients suspected of prostate cancer due to abnormal PSA or abnormal digital rectal examination, and both MRI and PSMA PET-CT suspected prostate cancer (PIRADS of MRI = 4; PET score = 4, five point Likert scale); 3.The clinical stage is T2-T3a, and there is no distant metastasis; 4.Agree to undergo radical prostatectomy after the diagnosis of prostate cancer by prostate biopsy, and can accept regular reexamination and follow-up after surgery.

Exclusion criteria

Exclusion criteria: 1.Severe cardiopulmonary and other related diseases and cannot tolerate surgery; 2.Had received endocrine therapy or pelvic radiotherapy before surgery; 3.Patients with previous prostate surgery; 4.Patients deemed unsuitable for inclusion by the investigator.

Design outcomes

Primary

Measure	Time frame
The accuracy of intraoperative frozen section in the diagnosis of prostate cancer;	—

Secondary

Measure	Time frame
positive surgical margins;	—

Countries

China

Contacts

Public ContactLiu Ming

Beijing Hospital

liuming19731029@163.com+86 13911036970

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026