Fracture
Conditions
Interventions
esmolamine group:esmolamine
continuous nerve block group:continuous nerve block
Sponsors
Department of Anesthesiology, affiliated Hospital of Yangzhou University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing hip fracture surgery at selected time; 2. Age 65 and above, regardless of gender; 3. ASA Class I-III; 4.BMI 18~30 kg/m2 5. No mental and nervous system diseases; 6. No pathological fracture, such as bone tumor, bone tuberculosis, osteomyelitis, etc; 7. No puncture site infection; 8. Plan to stay in hospital = 48 hours after surgery; 9. The patient requires to use the self controlled analgesia device after operation; 10. Clearly understand and voluntarily participate in the study, and sign the informed consent form by himself.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, liver and kidney dysfunction before operation; 2. Those who have taken analgesic and sedative drugs and alcoholism for a long time; 3. The patient was judged as having difficulty in managing respiratory tract (the modified Markovian score was Grade IV); 4. Previously suffered from severe cerebrovascular disease, Alzheimer's disease, epilepsy, Parkinson's disease and other neuropsychiatric diseases; 5. Previous history of intracranial surgery or brain injury; 6. Those who have serious vision, hearing, language disorders or are unable to communicate for other reasons; 7. Those who are allergic to or contraindicated to ropivacaine and non steroidal anti-inflammatory drugs (NSAID); 8. Emergency surgery or trauma patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of perioperative neurocognitive impairment;Postoperative quality of recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospitalization time;Postoperative complication; | — |
Countries
China
Contacts
Public ContactSun Jianhong
Affiliated Hospital of Yangzhou University
Outcome results
None listed