Intestinal diseases
Conditions
Interventions
test group:Linaclotide 290ug×1 tablet+compound polyethylene glycol electrolyte powder 68.56g×1 bag (1L) orally (21: 00 the night before colonoscopy)+linaclotide 290ug×1 tablet+compound polyethylene gl
control group:Compound polyethylene glycol electrolyte powder 68.56g×2 bags (2L) orally (21: 00 the night before colonoscopy)+compound polyethylene glycol electrolyte powder 68.56g×1 bags (1L) orally
Sponsors
Department of Gastroenterology, the First Affiliated Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.sign the informed consent form voluntarily; 2.Age 18 ~ 70 years old, male or female.
Exclusion criteria
Exclusion criteria: 1. Have a history of acute myocardial infarction or cerebrovascular accident (within 6 months), and have severe heart, lung, liver, kidney dysfunction and other basic diseases; 2. Those who are taking aspirin, warfarin and other anticoagulant drugs or have coagulation dysfunction; 3. Severe gastroparesis and intestinal obstruction after gastrointestinal resection; 4. Past or current severe constipation (it can be relieved by repeated use of laxatives/enema or physical intervention), and foreign body removal or decompression by colonoscopy; 5. Known or suspected gastrointestinal obstruction or perforation; 6. Pregnant or lactating women; 7. Persons with mental illness who cannot cooperate with the examination; 8. People who are allergic to intestinal preparations; 9. Patients judged by the investigator to be unsuitable for this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Boston bowel preparation score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient tolerance score;Patient compliance;Total defecation time (the night before colonoscopy);Number of defecation (the night before colonoscopy);Detection rate of intestinal polyps;Detection rate of intestinal adenoma;Cecal intubation rate;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactCai Xianbin
The First Affiliated Hospital of Shantou University Medical College
Outcome results
None listed