Residual symptoms of anxiety or depression disorders
Conditions
Interventions
Case series:None
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients with anxiety and depression: 1. 18-60 years old; 2. Meet the diagnostic criteria of DSM-V depression or anxiety disorder, HAMD = 14 points or HAMA = 14 points; 3. No contraindication of MRI, EEG and other examinations; 4. Right handedness; 5. The education level is primary school graduate or above, the mother tongue is Chinese, and the informed consent form is signed. Inclusion criteria for healthy controls: 1. 18-60 years old; 2. Healthy subjects; 3. No contraindication of MRI, EEG and other examinations; 4. Right handedness; 5. The education level is primary school graduate or above, the mother tongue is Chinese, and the informed consent form is signed.
Exclusion criteria
Exclusion criteria: Exclusion criteria for patients with anxiety and depression: 1. Mental disorders include schizophrenia, severe depression with suicidal tendency, alcoholism or other substance abuse; 2. Complicated with other system diseases that seriously affect the prognosis; 3. Patients with contraindications to antidepressants; 4. Aphasia, deafness, blindness, etc. cannot cooperate with the assessment or are combined with cognitive dysfunction; 5. Lactation period, pregnancy or pregnancy plan during the trial period; 6. Closed phobia, metal products in the body, etc. are not suitable for MRI examination; 7. Anxiety or depression caused by intracranial organic diseases. Exclusion criteria for healthy controls: 1. Emotional disorders include anxiety disorder, depression disorder, bipolar disorder, etc; 2. Mental disorders include schizophrenia, severe depression with suicidal tendency, alcoholism or other substance abuse; 3. Complicated with other system diseases that seriously affect the prognosis; 4. Aphasia, deafness, blindness, etc. cannot cooperate with the assessment or are combined with cognitive dysfunction; 5. Lactation period, pregnancy or pregnancy plan during the trial period; 6. Closed phobia, metal products in the body, etc. are not suitable for MRI examination; 7. Anxiety or depression caused by intracranial organic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Residual symptoms; | — |
Countries
China
Contacts
Public ContactYuan Yang
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed