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Effect of depth of anesthesia on postoperative delirium after major abdominal surgery in elderly patients with preoperative frailty: a randomized controlled trial

Effect of depth of anesthesia on postoperative delirium after major abdominal surgery in elderly patients with preoperative frailty: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057310
Enrollment
Unknown
Registered
2022-03-07
Start date
2022-03-10
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Light anesthesia:BIS target 35-40
Deep anesthesia:BIS target 50-55

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Elderly patients aged >=65 years; 2. ASA grade II-III; 3. Preoperative Fried Frailty Index >=2; 4. Undergoing major abdominal surgery (an expected duration >=2 h) with an anticipated postoperative hospital stay >=3 days.

Exclusion criteria

Exclusion criteria: 2. Patients with Alzheimer's disease, Parkinson's disease, preoperative cognitive impairment (MMSE score <= 23), visual and hearing impairment, illiteracy, and refusal to participation.

Design outcomes

Primary

MeasureTime frame
postoperative delirium;—

Secondary

MeasureTime frame
postoperative pain;postoperative fentanyl consumption;postoperative hospital stay;delayed neurocognitive recovery;postoperative neurocognitive disorder;—

Countries

China

Contacts

Public ContactJi Fuhai

The First Affiliated Hospital of Soochow University

jifuhai@suda.edu.cn+86 13656207331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026