Application of tissue oxygen saturation in evaluating tissue ischemic injury caused by tourniquet in lower limb surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200057300

Enrollment

Unknown

Registered

2022-03-07

Start date

2022-03-07

Completion date

Unknown

Last updated

2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tissue ischemic injury

Interventions

Gold Standard:Markers of tissue ischemic injury in blood

Index test:Tissue oxygen saturation

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Ages 18-60 years; 2. BMI 19-24 kg/m2; 3. Tourniquet operation is required for injuries or fractures of lower limb joints or soft tissues; 4. The amount of surgical bleeding is not expected to exceed 100 mL; 5. ASA I-II.

Exclusion criteria

Exclusion criteria: 1. Uncontrolled hypertension and peripheral vascular disease; 2. Thrombosis of lower extremity; 3. Severe skin diseases of lower limbs; 4. Tumor patients; 5. Diabetes mellitus and severe infection; 6. Previous history of vascular embolism; 7. Decline to attend.

Design outcomes

Primary

Measure	Time frame
Creatine Kinase;Myoglobin;	—

Secondary

Measure	Time frame
C-reactive protein;	—

Countries

China

Contacts

Public ContactHao Ning

Guangdong Provincial Hospital of Chinese Medicine

haoningmzk@163.com+86 13556101652

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026