Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged from 20 to 70 years; 2. The presence of visual emphysema confirmed by Low dose CT scan; 3. Patients who can tolerate or cooperate the pulmonary function tests.
Exclusion criteria
Exclusion criteria: 1. Presence of other acute or chronic respiratory diseases other than COPD, including bronchiectasis, lung infection, tumor, or the history of lung surgery; 2. Patients with a prior definitive diagnosis of COPD; 3. The presence of severe liver and kidney dysfunction; 4. The people suffered severe heart failure or malignant arrhythmias; 5. Acute cerebrovascular events within the past 3 months; 6. An uncured malignancy; 7. History of mental illness; 8. The state of lactation, pregnancy, or planned pregnancy; 9. Subjects who are not expected to cooperate and follow up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the percentage of low attenuation area, LAA%;Forced Expiratory Volume in One Second/Forced Vital Capacity, FEV1/FVC;Forced expiratory volume in one second as a percentage of the expected value, FEV1%pred; | — |
Countries
China
Contacts
The First Affiliated Hospital of Shandong First Medical University