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Comparison of the effects of selective a 1-receptor and non-selective a-receptor blockers on intraoperative hemodynamics in patients with pheochromocytoma and paraganglioma

Comparison of the effects of selective a1-receptor and non-selective a-receptor blockers on intraoperative hemodynamics and risk factors in patients with pheochromocytoma and paraganglioma: a retrospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200057291
Enrollment
Unknown
Registered
2022-03-07
Start date
2022-02-21
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative haemodynamic changes for patients with pheochromocytoma and paraganglioma

Interventions

None listed

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients who underwent surgery for PPGLs during the study period and had a postoperative pathological diagnosis of PPGLs confirmed.

Exclusion criteria

Exclusion criteria: 1. No preoperative preparation with any or both alpha-blockers; 2. Bilateral PPGLs; 3. Performing complex surgery or multiple procedures; 4. Incomplete information.

Design outcomes

Primary

MeasureTime frame
Hemodynamic instability score, HI-score;—

Secondary

MeasureTime frame
Postoperative 24-hour systolic blood pressure;Postoperative 24-hour heart rate;Total volume of infusion;Clavien-Dindo classification;Postoperative hospital stay;—

Countries

China

Contacts

Public ContactWensheng Zhang

West China Hospital of Sichuan University

zhang_ws@scu.edu.cn+86 18980601564

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026