schizophrenia
Conditions
Interventions
Healthy control group:None
TMS stimulation group:Transcranial magnetic stimulation treatment
Pseudo TMS stimulation group:Pseudo-transcranial magnetic stimulation treatment
Sponsors
Beijing Anding Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Chinese Han nationality, right-handed, 18-45 years, junior high school education or above, normal intelligence test (IQ >= 75); 2. The patient was interviewed by a clinician at or above the attending physician level and determined to meet the DSM-IV diagnostic criteria for schizophrenia; 3. The patient's symptoms have been stable for more than 2 weeks after treatment with stable dose drugs; 4. No history of major physical diseases, craniocerebral trauma, no history of epilepsy or family history, no MRI contraindications; 5. Patient Health Questionnaire-9 (PHQ-9) score >= 10; 6. The subject is willing to participate in the study, and the subject and his legal guardian jointly sign the informed consent; 7. Healthy volunteers have no history of alcohol and drug abuse; 8. Healthy volunteers had no family history of neurological diseases (except cerebrovascular accidents); 9. The healthy volunteers had no current history of clearly diagnosed neurological and other serious physical disorders.
Exclusion criteria
Exclusion criteria: 1. Patients with nuclear contraindications such as metal implants such as dentures, arterial clips, pacemakers or metal fixators in the body; 2. Claustrophobic and unable to cooperate with the completion of the magnetic test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| brain functional connectivity;event-related potentials;positive and negative syndrome scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| MATRICS consensus cognitive battery;Calgary depression scale for schizophrenia; | — |
Countries
China
Contacts
Public ContactLi Jun
Beijing Anding Hospital
Outcome results
None listed