Neonatal respiratory distress syndrome
Conditions
Interventions
Group 1 :Vibrating mesh atomization
Group 2:intubation-surfactant-extubation
Sponsors
The First Affiliated Hospital of Bengbu Medical College
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Preterm infants with gestational age < 37 weeks; 2. Meet the diagnostic criteria of RDS, 5th edition of Practical Neonatology, that is, progressive dyspnea occurs after birth, which is manifested as cyanosis, groan, trisogal sign and shortness of breath, and may further develop into respiratory failure; at the same time, lung X-ray typical findings such as ground-glass changes, air bronchogram or white lung, and other causes of respiratory distress were excluded.
Exclusion criteria
Exclusion criteria: 1. Involuntary breathing; 2. Progressive exacerbation of respiratory distress, failure to maintain oxygen saturation (FiO2 > 0.40, Pa02 60 mmHg, pH < 7.25); 3. Congenital malformations: including posterior nasal atresia, cleft palate, congenital diaphragmatic hernia, tracheoesophageal fistula, etc.; 4. Unstable cardiovascular system: such as cardiac insufficiency, hypotension, tissue hypoperperfusion, etc.; 5. Others: emphysema, pneumothorax, gastrointestinal bleeding, severe abdominal distension, local injury (including nasal mucosa, mouth and face).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index;pondus hydrogenii, pH;Partial pressure of carbon dioxide, PaCO2;duration of respiratory support; | — |
Countries
China
Contacts
Public ContactXin Chen
The First Affiliated Hospital of Bengbu Medical College
Outcome results
None listed