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Effect of oxycodone on visceral pain after laparoscopic major gastrointestinal surgery: a multicenter, randomized, double-blind, controlled trial

Effect of oxycodone on visceral pain after laparoscopic major gastrointestinal surgery: a multicenter, randomized, double-blind, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057267
Enrollment
Unknown
Registered
2022-03-05
Start date
2022-06-01
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain treatment

Interventions

Group 1 :Oxycodone

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. ASA: I-III grade; 3. Patients who intend to undergo major laparoscopic gastrointestinal surgery under general anesthesia (defined as operation time >= 120 minutes, involving at least partial resection of the stomach or intestine).

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; 2. BMI >= 35 kg/m2; 3. Severe cardiopulmonary diseases, severe cerebrovascular diseases, severe liver and kidney diseases (Child-Pugh C grade, renal replacement therapy), neurocognitive disorders (MMSE <= 23); 4. Use of antipsychotics, alcoholism, chronic opioids or other analgesic drugs; 5. Unable to understand the rating scale; 6. Allergy to the drug under study; 7. Refuse to participate.

Design outcomes

Primary

MeasureTime frame
visceral pain at rest during 1-24 h postoperatively;

Secondary

MeasureTime frame
visceral pain on coughing during 1-24 h postoperatively;visceral pain scores at rest and on coughing at each timepoint;incisional pain scores at rest and on coughing at each timepoint;shoulder pain scores at rest and on coughing at each timepoint;postoperative analgesic consumption;Quality of Recovery Questionnaire 15, QoR-15;overall patient satisfaction with analgesia;length of postoperative stay;persistent pain after surgery;mortality;rescue analgesia;

Countries

China

Contacts

Public ContactFuhai Ji

The First Affiliated Hospital of Soochow University

jifuhaisuda@163.com+86 13656207331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026