Postoperative pain treatment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. ASA: I-III grade; 3. Patients who intend to undergo major laparoscopic gastrointestinal surgery under general anesthesia (defined as operation time >= 120 minutes, involving at least partial resection of the stomach or intestine).
Exclusion criteria
Exclusion criteria: 1. Emergency surgery; 2. BMI >= 35 kg/m2; 3. Severe cardiopulmonary diseases, severe cerebrovascular diseases, severe liver and kidney diseases (Child-Pugh C grade, renal replacement therapy), neurocognitive disorders (MMSE <= 23); 4. Use of antipsychotics, alcoholism, chronic opioids or other analgesic drugs; 5. Unable to understand the rating scale; 6. Allergy to the drug under study; 7. Refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visceral pain at rest during 1-24 h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| visceral pain on coughing during 1-24 h postoperatively;visceral pain scores at rest and on coughing at each timepoint;incisional pain scores at rest and on coughing at each timepoint;shoulder pain scores at rest and on coughing at each timepoint;postoperative analgesic consumption;Quality of Recovery Questionnaire 15, QoR-15;overall patient satisfaction with analgesia;length of postoperative stay;persistent pain after surgery;mortality;rescue analgesia; | — |
Countries
China
Contacts
The First Affiliated Hospital of Soochow University