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Clinical study on modified Cangma Decoction in the treatment of airway mucus hypersecretion in bronchiectasis

Clinical study on modified Cangma Decoction in the treatment of airway mucus hypersecretion in bronchiectasis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057265
Enrollment
Unknown
Registered
2022-03-05
Start date
2022-03-15
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchiectasis

Interventions

Experimental group:modified Cangma Decoction
Control group:oral liquid of Carbocysteine

Sponsors

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the above diagnosis of bronchiectasis and airway mucus hypersecretion; 2. Patients who meet the above diagnosis of spleen deficiency and phlegm dampness syndrome; 3. Older than 18 years and younger than 80 years; 4. The original score of casa-q expectoration symptom domain is greater than or equal to 4 points.

Exclusion criteria

Exclusion criteria: 1. Liver function ALT > 75 U/L, AST > 60 U/L, TBIL > 30.75 umol/l; renal function in patients with Cr > 15 mmol/L; 2. Complicated with serious cardiovascular and cerebrovascular complications and serious gastrointestinal diseases; 3. Patients with various organ tumors; 4. Pregnant and lactating women; 5. Patients with severe mental illness; 6. Known allergy to test drug; 7. Participated in other clinical trials within three months.

Design outcomes

Primary

MeasureTime frame
score of CASA-Q;

Secondary

MeasureTime frame
number of acute exacerbations within 3 months;blood routine;c reactive protein;

Countries

China

Contacts

Public ContactXitong Liu

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University

liuxitong@bjzhongyi.com+86 13521431010

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026