tumor
Conditions
Interventions
Experimental group:huaweiyi probiotics
Sponsors
The Second People's Hospital of Neijiang
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18-75 years, male or female; 2. Patients with solid tumors confirmed by histopathology and/or cytology with stage III-IV imaging; 3. ECOG PS: 0-3 points; 4. Expected survival >= 1 month; 5. No opioid analgesic treatment was performed in the past, and the NRS score was moderate to severe cancer pain. The physician planned to use morphine hydrochloride (sulfuric acid) sustained release tablets for treatment; patients who had previously received opioid analgesic therapy should be eluted for 1 month and then treated with morphine hydrochloride (sulfate) sustained release tablets again. 6. The patients participated in the study voluntarily and signed the informed consent (ICF).
Exclusion criteria
Exclusion criteria: 1. Colon cancer, rectal cancer; 2. Multiple factors affecting the absorption of oral drugs (such as inability to swallow, nausea and vomiting, and intestinal obstruction); 3. Patients with chronic constipation; 4. Patients who have received surgery, radiotherapy, chemotherapy, targeted therapy, immunotherapy, Chinese patent medicine or Chinese herbal therapy within 28 days and may cause digestive tract reactions; 5. Other patients deemed unsuitable for inclusion by the treating physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| constipation; | — |
Secondary
| Measure | Time frame |
|---|---|
| nausea;vomit;abdominal distention;appetite; | — |
Countries
China
Contacts
Public ContactGuomiao Li
The Second People's Hospital of Neijiang
Outcome results
None listed