Esophageal cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 18 years <= age <= 85 years, no gender limitation; 2. All patients were diagnosed with esophageal cancer by gastroscopic pathology before surgery, and the tumor was located in the thoracic or abdominal esophagus and received surgical treatment; 3. Patients with T1-2N0-1M0 stage confirmed by ultrasound gastroscope before operation; or patients with T3N1M0(IIIa) stage who have achieved PR (partial response) after neoadjuvant radiotherapy/chemotherapy, and can undergo surgical resection; 4. Conduct chest CT, abdominal CT, cranial magnetic resonance imaging, whole-body bone scintigraphy or positron emission computed tomography, and the tumor has not invaded surrounding vital organs and distant metastasis; 5. The main organ functions are basically normal: the lung function is basically normal, and general anesthesia is acceptable; the NYHA classification of cardiac function is 0-1; 6. Voluntarily sign the informed consent form before the study, the patients and/or their legal representatives have the ability to fully understand the trial content, process and possible adverse reactions, and enable the patients to comply with the visits prescribed by the protocol; 7. Women of childbearing age must have a negative pregnancy test and not be breastfeeding, and confirm that both male and female patients are receiving contraceptive methods approved by the investigator, and agree to maintain this contraceptive measure from the time of signing the informed consent form to 3 months after the end of the study.
Exclusion criteria
Exclusion criteria: 1. Patients with malignant tumors in other parts at the same time; 2. Patients with a history of esophagectomy or gastrectomy; 3. Patients with a history of mediastinal surgery or extensive abdominal adhesions; 4. Patients with cardiac thrombosis; 5. Those who suffer from mental, mental or nervous system diseases; 6. Patients with cachexia and severe malnutrition; 7. Recent history of gastric ulcer recurrence, gastric bleeding and other serious underlying diseases; 8. Patients with surgical contraindications such as coagulation dysfunction, HIV antibody positive, and severe infection with poor clinical control; 9. Patients with other concomitant diseases (such as abnormal liver and kidney function, etc.) or concomitant medication, which may have an impact on the results of this study as judged by the investigator; 10. Patients who participate in another clinical study at the same time; 11. Patients who are known to be allergic to the material of surgical instruments, or have an allergic constitution; 12. Others judged by the investigator to be unsuitable to participate in this clinical trial; 13. Those who refuse to cooperate with ERAS treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6 minute walk test;Diaphragmatic activity;Lung ventilation test;blood gas analysis; | — |
Countries
China
Contacts
The Fifth Affiliated Hospital of Sun Yat-Sen University