Parkinson's disease
Conditions
Interventions
Group A: rTMS true stimulation group:TMS stimulation
Group B: electroacupuncture stimulation group:Electroacupuncture stimulation
Group C: electroacupuncture non-acupoint stimulation group:Electroacupuncture non-acupoint stimulation
Group D: rTMS sham stimulation group:rTMS sham stimulation
Sponsors
Xuanwu Hosptial of Captial Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 to 85 years; 2. PD patients with pain, excluding patients with apparent tumors, diabetes, osteoarthritis, rheumatoid disease, lumbar disc herniation, and other comorbidities that can explain the pain, among which PD patients. The diagnostic criteria are based on the 2015 MDS clinical diagnostic criteria, and the PD patients are diagnosed as "clinically confirmed" or "probable"; 3. H-Y stage: I-IV stage.
Exclusion criteria
Exclusion criteria: 1. Secondary Parkinsons syndrome caused by vascular factors, toxins, drugs, etc., or Parkinsons superimposed syndrome; 2. PD patients with persistent head tremor; 3. Dementia, Mini-Mental State Examination (MMSE) <= 24 points; 4. Patients with suicidal tendencies and psychotic symptoms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Magnetic Resonance Imaging;Numerical Rating Scale;Simple McFarland Pain Questionnaire;International Movement Disorders Association Unified Parkinson's Disease Rating Scale Part III;International Movement Disorders Association Unified Parkinson's Disease Rating Scale Part IV;King's Parkinson’s Disease Pain Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroencephalogram; | — |
Countries
China
Contacts
Public ContactLi Jun
The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Outcome results
None listed