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Driving pressure-guided ventilation in patients undergoing laparoscopic sleeve gastrectomy: a prospective randomized controlled trial

Driving pressure-guided ventilation in patients undergoing laparoscopic sleeve gastrectomy: a prospective randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057246
Enrollment
Unknown
Registered
2022-03-04
Start date
2022-02-28
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung

Interventions

Group B:driving pressure-guided ventilation strategy

Sponsors

Zhengzhou Central Hospital Affiliated To Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. There is no limit on the gender; 2. Aged 18 to 60 years; 3. ASA grade II-III; 4. BMI > 30 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Preoperative Hb was lower than 110 g/L; 2. Preoperative coagulation was abnormal; 3. History of upper respiratory tract infection within 2 weeks before surgery; 4. Preoperative CT showed atelectasis or severe respiratory disease; 5. Associated neurological disease or previous history of cerebrovascular disease; 6. Accompanied by serious heart, liver, kidney and other systemic diseases; 7. Refused to sign informed consent.

Design outcomes

Primary

MeasureTime frame
driving pressure;

Secondary

MeasureTime frame
Respiratory compliance;Tidal volume;Mean arterial pressure, MAP;Heart rate, HR;End-expiratory carbon dioxide concentration, PetCO2;Platform pressure, Pplat;Peak pressure, Ppeak;Temperature, T;Incidence of postoperative pulmonary complications (PPCs);Infusion volume;Bleeding volume;urine volume;Surgery time;Anesthesia time;

Countries

China

Contacts

Public ContactQinjun Chu
jimmynetchu@163.ccom+86 13643711142

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026