stroke
Conditions
Interventions
Cerebellum-M1 group:transcranial magnetic stimulation (TMS)
Cerebellum-SMA group:transcranial magnetic stimulation (TMS)
Cerebellum-cerebellum group:transcranial magnetic stimulation (TMS)
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-75 years; 2. The first occurrence of unilateral hemispheric subcortical stroke, the course of disease >= 1 month; 3. The diagnosis met the criteria of "Key Points for the Diagnosis of Various Cerebrovascular Diseases in China" in 2019; 4. Motor dysfunction; 5. The condition is stable, conscious, and vital signs are stable; 6. Willing to cooperate with examination, intervention and follow-up; 7. The informed consent is signed by the patient himself or by his legal representative or guardian.
Exclusion criteria
Exclusion criteria: 1. Patients with serious primary diseases of heart, liver, kidney and hematopoietic system; 2. Patients with limb motor dysfunction caused by other non-cerebrovascular pathogens (such as peripheral nerve injury, spinal cord injury, fracture, congenital joint deformity, etc.); 3. Patients with a history of mental disorders or drug abuse; 4. Patients with previous history of epilepsy, metal implants in the brain that cannot be removed, skull defects and other contraindications of TMS; 5. May cause unpredictable influence on the research results; 6. Pregnant and lactating women; 7. Those who are not expected to complete the trial and have poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Berg Balance Scale;Fugl-meyer assessment of motor function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Action Research Arm Test, ARAT;Modified Barthel Index;functional comprehensive assessment;Functional Near Infrared Spectrum Instrument; | — |
Countries
China
Contacts
Public ContactHu Ruiping
Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University
Outcome results
None listed