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Effect of roxadustat on iron metabolism in peritoneal dialysis patients

Effect of roxadustat on iron metabolism in peritoneal dialysis patients

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200057231
Enrollment
Unknown
Registered
2022-03-04
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic kidney disease

Interventions

Roxadustat:no intervention
Erythropoietin:no intervention

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years; 2. Regular peritoneal dialysis for at least 6 weeks; 3. Within 6 weeks, the patient did not receive erythropoietin, roxadustat or iron supplementation. 4. Mean HB70-100g /L (mean of two most recent Hb measurements taken at least one week apart during screening and prior to enrollment, absolute difference <= 10g/L between the two measurements).

Exclusion criteria

Exclusion criteria: 1. Change the dialysis method or combine with other dialysis methods; 2. Serious organic dysfunction of heart, liver, lung and brain; 3. Pregnant and lactation women; 4. Incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
Hepcidin;serum transferrin receptor;ferritin;iron transporter saturation;

Secondary

MeasureTime frame
total iron binding capacity;unsaturated iron-binding capacity;Hemoglobin;reticulocyte count;Erythropoietin;serum creatinine;estimated glomerular filtration rate;serum potassium;total cholesterol;Triglyceride;high-density lipoprotein;Low density lipoprotein;

Countries

China

Contacts

Public ContactSun Dong

Affiliated Hospital of Xuzhou Medical University

sundongxz@126.com+86 18952186599

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026