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Efficacy of collagen sponge on palatal wound healing: a randomized controlled clinical trial

Efficacy of collagen sponge on palatal wound healing: a randomized controlled clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057221
Enrollment
Unknown
Registered
2022-03-04
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healing of palatal wound

Interventions

Experimental group:collagen sponge

Sponsors

The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. Clinical indications utilizing free gingival grafts or de-epithelialized gingival grafts to treat either insufficient keratinized tissue or gingival recession defects; 3. Full-mouth plaque score and full-mouth bleeding score lower than 20%.

Exclusion criteria

Exclusion criteria: 1. Smoking; 2. Pregnancy or lactation; 3. Untreated periodontal disease; 4. Severe systemic conditions that contraindicate surgery (diabetes, heart disease, cancer etc.); 5. Presence of coagulation disorders (history of haemophilia, von Wille- brand disease, or anticoagulant therapy); 6. Taking medications affecting periodontal health or healing; 7. Previous surgery for a palate graft harvested from the experimental sites.

Design outcomes

Primary

MeasureTime frame
epithelialization of the palatal wound;

Secondary

MeasureTime frame
postoperative pain;willingness to repeat the treatment;the existence of delayed bleeding;aesthetic score;consumption of analgesics;

Countries

China

Contacts

Public ContactPeihui Ding

The Affiliated Stomatology Hospital of Zhejiang University School of Medicine

phding@zju.edu.cn+86 18957108518

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026