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Injectable cartilage regenerated from autologous chondrocytes for the correction of cleft lip and palate and nasal floor deformity

Injectable cartilage regenerated from autologous chondrocytes for the correction of cleft lip and palate and nasal floor deformity

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057212
Enrollment
Unknown
Registered
2022-03-03
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative deformity of cleft lip and palate

Interventions

Experimental group:Tissue-engineered cartilage was injected to fill the nasal base depression

Sponsors

Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. The first diagnosis must be consistent with cleft lip and palate deformity; 2. Aged 18-50 years; 3. In good health, no previous systemic diseases or sexually transmitted diseases.

Exclusion criteria

Exclusion criteria: 1. Poor overall state; 2. Failure of vital organs such as heart, lung, brain and kidney; 3. Blood disease or bleeding tendency; 4. Drug addiction (including drug, anesthetic and alcohol addiction); 5. Infectious viral infections; 6. Patients with systemic or local infectious lesions; 7. Patients during pregnancy or lactation; 8. Suffering from psychological disorders and unable to cooperate with rehabilitation treatment; 9. Patients with abnormal development of important organs or other organs; 10. Patients who are participating in programs for the clinical use of other technologies.

Design outcomes

Primary

MeasureTime frame
CT three-dimensional reconstruction;Three dimensional laser scanning;

Secondary

MeasureTime frame
Blood routine examination;C-reactive protein;Maxillofacial infection;General picture;

Countries

China

Contacts

Public ContactZhou Guangdong
guangdongzhou@126.com+86 13818248439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026