Diminished Ovarian Reserve
Conditions
Interventions
Intervention group:Injection of PRP
Control group:None
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. AFC =6 months without contraception; 3. The number of oocytes obtained by the previous standard regimen (antagonist and long regimen) was <=3; 4. The patient or his legal representative signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Hydrosalpinx: ultrasound or salpingography may indicate hydrosalpinx; 2. Adenomyosis: ultrasound /MRI diagnosis of adenomyosis with or without serum CA125 elevation; 3. Endometriosis: previous definite surgical diagnosis of endometriosis, or repeated ultrasound findings (>=3 times) of ovarian hypoecho; 4. Severe oligoasthenospermia/azoospermia; 5. Uterine malformations: unichorned uterus, bichorned uterus, mediastinal uterus; 6. Metabolic diseases: diabetes mellitus, hyperthyroidism, hypothyroidism untreated; 7. Obesity: BMI > 28; 8. Thin: BMI =3 or transfer embryos >=4; 10. Systemic diseases cannot tolerate IVF embryo transfer: serious cardiovascular and cerebrovascular diseases, blood system diseases and other organ diseases, whose specialist doctors do not recommend pregnancy; 11. Systemic diseases can not pregnancy: serious cardiovascular and cerebrovascular diseases, blood system diseases and other organ diseases, whose specialist doctors do not recommend pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| number of eggs retrieved;2PN fertilization rate;available embryo rate;biochemical pregnancy rate;clinical pregnancy rate;ongoing pregnancy rate;miscarriage rate;embryo implantation rate;cycle cancellation rate; | — |
Countries
China
Contacts
Public ContactWang Yanbin
Outcome results
None listed