infertility
Conditions
Interventions
Experimental group:On the second day of menstruation, FSH was recombined at a starting dose of 225-300 U and rLH was added in a 2:1 ratio according to the patient s BMI and AFC (75urLH at 225u initiat
Control group:On the second day of menstruation, FSH was reconstituted at an initial dose of 225-300 U according to the patient s BMI and AFC. On day 6 of ovulation induction, rLH was added in a 2:1 r
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
Female
Age
35 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 35 years; 2. AFC>=5; AMH >= 1.2 ng/ml; Oocyte retrieval cycle >= 2 times; 3. Full start-up of the standard solution in the previous cycle (Gn: 300u); No more than 9 oocytes were retrieved.
Exclusion criteria
Exclusion criteria: 1. Hydrosalpinx: ultrasound or salpingography may indicate hydrosalpinx; 2. Adenomyosis: ultrasound /MRI diagnosis of adenomyosis with or without serum CA125 elevation; 3. Endometriosis: previous definite surgical diagnosis of endometriosis, or repeated ultrasound findings (>=3 times) of ovarian hypoecho; 4. Severe oligoasthenospermia/azoospermia; 5. Uterine malformation: single horn uterus, double horn uterus, uterus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| persistent pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| number of retrieved oocytes;2PN fertilization rate;available embryo rate;blastocyst formation rate;biochemical pregnancy rate;clinical pregnancy rate;abortion rate;implantation rate;cycle cancellation rate;rate of no avaitable embryos; | — |
Countries
China
Contacts
Public ContactWang Yanbin
Peking University People's Hospital
Outcome results
None listed