Allergic rhinitis
Conditions
Interventions
Gold Standard:Patients with allergic rhinitis (according to ARIA criteria) had a skin prick test or serum specific IgE of grade 3 or higher.
Index test:The kappa coefficient of the rhinitis classification of patients diagnosed by traditional methods and the rhinitis classification of patients diagnosed by kit test during the screening peri
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
3 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 3-60 years; 2. Patients who met any of the following criteria: patients with allergic rhinitis (according to ARIA criteria), skin prick test or serum specific IgE grade 3 or higher; 3. The patient agreed to participate in the trial and signed the informed consent form; 4. Patients who met the protocol requirements as judged by the investigator.
Exclusion criteria
Exclusion criteria: 1. Patients with nasal mucosa erosion, nasal mucosa ulcer and nasal septum perforation found by nasal examination; 2. Patients who used anticoagulant drugs within 5 days; 3. Nasal surgery in the past month; 4. Patients with other nasal diseases that may lead to drug deposition in the nasal cavity, such as sinusitis, drug-induced rhinitis, nasal polyps, or nasal structural abnormalities; 5. Patients with non-allergic rhinitis (vasomotor rhinitis, eosinophilia rhinitis); 6. Patients who underwent nasal surgery within 90 days before the start of the observation period were screened; 7. Patients with contraindications to desensitization; 8. Patients with recurrent epistaxis; 9. Patients suffering from complications such as severe liver disease, kidney disease, heart disease or blood disease; 10. Patients with alcohol or substance abuse/addiction conditions that may affect the progress of the study. Binge drinking is the consumption of more than 14 units of alcohol per week (1 unit of alcohol =360 mL of beer, 45 mL of spirits with a 40% alcohol concentration, or 150 ml of wine); 11. Systemic or local use of antibiotics, nasal spray hormones, nasal spray or oral antihistamines within 1 week before sampling, and systemic use of corticosteroids or immunosuppressants 3 weeks before sampling; 12. Upper respiratory tract infection or other acute infection within 30 days; 13. Patients judged by the investigator to be inappropriate subjects for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The kappa coefficient of the rhinitis classification of patients diagnosed by traditional methods and the rhinitis classification of patients diagnosed by kit test during the screening period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptom score;Serological test;Detection of nasal secretions; | — |
Countries
China
Contacts
Public ContactTao Zezhang
Renmin Hospital of Wuhan University
Outcome results
None listed