pneumoconiosis
Conditions
Interventions
Control group:Conventional treatment and placebo
Experimental group:Conventional treatment + double bronchodilator
Sponsors
The 920th Hospital of the Joint Logistics Support Force of the People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. According to the diagnosis of occupational pneumoconiosis in China (GBZ 70 -- 2015), the patient was diagnosed as pneumoconiosis; 2. Pulmonary function showed patients with ventilation dysfunction, that is, pulmonary function tests suggested (FEVl >= 50%, but =60 mL/ year); 3. mMRC Dyspnea Scale 1 - 2; 4. Aged 18-80 years, agree to participate in this research.
Exclusion criteria
Exclusion criteria: 1. Asthma, long-term use of hormones, allergy to ummeteronium/vilanterol; 2. Patients with acute myocardial infarction or NYHA class IV; 3. After disease control, bronchodilator should be stopped for <=4 weeks; 4. Patients with malignant tumors and severe systemic diseases who cannot complete the treatment; 5. Special population: severe mental abnormality cannot cooperate with patients and pregnant patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| forced expiratory volume in 1st second; | — |
Secondary
| Measure | Time frame |
|---|---|
| lung capacity;forced vital capacity;1 second rate;peak expiratory flow;maximum expiratory 25% vital capacity instantaneous flow;maximum expiratory 50% vital capacity instantaneous flow;maximum expiratory 75% vital capacity instantaneous flow;maximum mid-expiratory flow;questionnaire survey data; | — |
Countries
China
Contacts
Public ContactLi Shaoying
Outcome results
None listed