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Multi-angle evaluation of the advantages and disadvantages of different postoperative analgesia methods for total knee replacement: A randomized, controlled trial

Multi-angle evaluation of the advantages and disadvantages of different postoperative analgesia methods for total knee replacement: A randomized, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057200
Enrollment
Unknown
Registered
2022-03-03
Start date
2019-09-01
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis, etc.

Interventions

group PCIA :2ug/kg+ dezocine 20mg+ dolasetron 25mg, diluted to 100mL by adding normal saline, no loading volume was set, background infusion rate was set as 2mL/h, and blous volume was 0.5ml/ time
group PCEA :0.1% ropivacaine, load set at 10mL, background infusion rate of 5mL/h, locking time of 20min, blous dose of 5ml/ time
group CFNBA :0.1% ropivacaine, loading volume 10ml, background infusion rate 5ml/h, locking time 20min, blous volume 5ml/ time

Sponsors

Quanzhou First Hospital Affiliated to Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Those who meet the relevant diagnostic criteria for knee joint diseases; 2. Patients with TKA treatment indications; 3. ASA GradeI-II; 4. Approved by the ethics committee of our hospital; 5. Those who voluntarily signed the informed consent; 6. Patients with normal preoperative coagulation function; 7. Patients without lower extremity venous thrombosis before operation; 8. No contraindications of anticoagulant drugs; 9. No intraspinal block contraindicated.

Exclusion criteria

Exclusion criteria: 1. Patients with mental diseases, hearing disorders, language disorders, and confusion; 2. Acute inflammatory skin disease; 3. Poor general condition, unable to tolerate surgery; 4. Withdrawal from treatment, change of surgical method, death or loss of contact during follow-up; 5. Patients with inadequate treatment compliance.

Design outcomes

Primary

MeasureTime frame
pain score;Adverse reactions;

Secondary

MeasureTime frame
coagulation indicators;the incidence of deep vein thrombosis in the lower extremities;

Countries

China

Contacts

Public ContactZeng Jingyang

Quanzhou First Hospital Affiliated to Fujian Medical University

serendipity1221@126.com+86 13860728258

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026