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The effect of dorsolateral prefrontal cortex on pain perception and cognition: A randomized controlled study based on tDCS

The effect of dorsolateral prefrontal cortex on pain perception and cognition: A randomized controlled study based on tDCS

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057181
Enrollment
Unknown
Registered
2022-03-02
Start date
2022-02-20
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Low Back Pain

Interventions

Anodal group:Transcranial direct current stimulation anodic stimulation
Cathodal group:Transcranial direct current stimulation cathodic stimulation
Sham group:Transcranial direct current stimulation sham stimulation

Sponsors

Shanghai University of Sport
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria of healthy subjects: (1) Healthy adults aged 18-35, right-handed; (2) No strong emotional fluctuation in the past week; (3) Normal cognitive function, able to understand the experimental process and cooperate to complete the experiment; (4) Vision is normal or corrected to normal; (5) Participate voluntarily and sign written informed consent. 2. Inclusion criteria of chronic low back pain: (1) Aged between 18 and 35, right-handed; (2) The range of pain is below the edge of the low rib to the area above the hip line, with muscle tension or stiffness, and may be accompanied by lower limb pain; (3) Low back pain in the past 3 months at least, and the pain is moderate or higher (VAS>=3); (4) Voluntarily participate and sign the informed consent; (5) Accept randomization.

Exclusion criteria

Exclusion criteria: 1. Exclusion criteria for healthy subjects: (1) The presence of paresthesia disease, obvious skin damage, skin diseases (affecting the measurement of pain); (2) The presence of neurological or mental illness (such as depression, anxiety, etc.); (3) Currently taking medication (such as antidepressants, painkillers, etc.). 2. Exclusion criteria for subjects with chronic low back pain: (1) Have received guided physical therapy for LBP in the past 3 months, including stretching, strength training and motor control training; (2) Patients with LBP with clear etiology and underlying pathological changes (e.g., sciatica, spinal stenosis, spondylolisthesis, recent vertebral fractures, etc.); (3) The pain in other parts of the body is more serious than the lower back pain; (4) Back surgery in the past 6 months; (5) Contact skin diseases, ulcers or open wounds.

Design outcomes

Primary

MeasureTime frame
Pain perception;

Secondary

MeasureTime frame
Executive function;Cortical hemodynamic changes;

Contacts

Public ContactWang Xueqiang
wangxueqiang@sus.edu.en+86 18601612741

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026