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Comparison of stone clearance between percutaneous nephrolithotomy under local anesthesia and percutaneous nephrolithotomy under general anesthesia for upper urinary calculi - randomized, controlled clinical trial

Comparison of stone clearance between percutaneous nephrolithotomy under local anesthesia and percutaneous nephrolithotomy under general anesthesia for upper urinary calculi - randomized, controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057173
Enrollment
Unknown
Registered
2022-03-02
Start date
2022-02-28
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary calculus

Interventions

Experimental group:percutaneous nephrolithotomy under local anesthesia
Control group:percutaneous nephrolithotomy under general anesthesia

Sponsors

Zhujiang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >18 years, no gender limit; 2. Complete and incomplete staghorn stones, renal stones >=2cm, symptomatic calyces or diverticular stones, stones that are difficult to be crushed by extracorporeal shock wave and those that fail to be treated; 3. Stones of the upper ureter above L4, > 1.5cm; Or ureteral calculi due to polyp wrapping and ureteral tortuousness, ineffective ESWL or failure of ureteroscopy placement; 4. American Society of Anesthesiology (ASA) Scale 1-3; 5. Those who voluntarily sign the informed consent form and are willing to be followed up.

Exclusion criteria

Exclusion criteria: 1. Anatomical abnormalities of the urinary system and skeletal malformations; 2. Fever or pyonephrosis, need to first suffer from kidney puncture and drainage; 3. Coagulopathy, being treated with anticoagulant or antithrombotic drugs; 4. Combined with ipsilateral middle and lower ureteral calculi or ureteral stricture; 5. Pregnancy; 6. The investigator considered it inappropriate to participate in this clinical study.

Design outcomes

Primary

MeasureTime frame
Stone clearance rate;

Secondary

MeasureTime frame
Postoperative complications;

Countries

China

Contacts

Public ContactLi Hulin
13380092166@163.com+86 13380092166

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026