Predictive effect of resting pupil light reflex on hypotension after induction of anaesthesia

Predictive effect of pupillary light reflex on hypotension after induction of anesthesia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200057164

Enrollment

Unknown

Registered

2022-03-01

Start date

2022-03-01

Completion date

Unknown

Last updated

2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension after induction

Interventions

case series:None

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Elective general anesthesia; 2. ASA Stage I-II; 3. Aged 18-65 years.

Exclusion criteria

Exclusion criteria: 1. Use drugs that affect pupil size (scopolamine, etc.); 2. Eye diseases (cataract, glaucoma, etc.); 3. Ocular surgery history; 4. Pupil deformity; 5. Neuromuscular dysfunction; 6. Taking alpha and beta blockers; 7. Hypertension and diabetes; 8. Thyroid dysfunction; 9. Operation time < 30min; 10. Lateral and prone position surgery; 11. Neurosurgery.

Design outcomes

Primary

Measure	Time frame
Maximum Constriction Velocity;Pupil Constriction Time;Baseline Pupil Diameter;Minimum Pupil Diameter;Constriction Ratio;Average Constriction Velocity;	—

Secondary

Measure	Time frame
Mean Arterial Pressure at Baseline;Baseline Heart Rate;Heart Rate at Lowest Mean Arterial Pressure;Minimum Mean Arterial Pressure;	—

Countries

China

Contacts

Public ContactDuan Manlin

dml9001@nju.edu.cn+86 25 80860114

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026