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Clinical exploration of bronchoscopic infusion of autologous repairing airway epithelial cells for interstitial lung disease

Clinical study on the treatment of interstitial lung disease by bronchoscopic infusion of self repairing airway epithelial cells

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057121
Enrollment
Unknown
Registered
2022-02-28
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interstitial lung disease (ILD)

Interventions

low dose group:1×10^6/kg cells
high dose group:2×10^6/kg cells

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with imaging findings consistent with ILD; 2. Aged >18 years and <=80 years, no gender limit; 3. Good compliance, healthy mental state, able to cooperate with research and observation; 4. No complications (acute infection, heart failure, hepatitis, nephritis); 5. Fully informed of the purpose, methods and possible discomfort of the study, agreed to participate in the study, and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who cannot tolerate cell therapy; 2. Participate in other drug trials 3 months before enrollment; 3. Pregnant or lactating patients or those who have a recent birth plan and cannot take effective contraceptive measures; 4. If there is anything that the researcher considers inappropriate for inclusion.

Design outcomes

Secondary

MeasureTime frame
high resolution computed tomography (CT)T;treatment endpoint events;

Primary

MeasureTime frame
lung function;6 minutes walk test;St George's score;

Countries

China

Contacts

Public ContactRen Tao

Shanghai Sixth People's Hospital

shanshan_shcn@126.com+86 18930177191

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026