Giant pituitary tumor
Conditions
Interventions
Artificial bone material filling group:Artificial bone material filling
Control group:None
Sponsors
The Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The diagnostic criteria of giant pituitary adenomas were evaluated according to MRI/CT examination in the sellar region: Pituitary tumor diameter >=3cm; 2. Age >=18 years old and <=70 years old; 3. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Complicated with severe infection, trauma, acute myocardial infarction, hypotension, hypoxia, and other stress conditions; 2. serious cardiovascular disease, untreated hypertension, and pulmonary insufficiency; 3. severe erosion of skull base or craniotomy is required; 4. Recurrent patients with a history of craniotomy or transnasal sphenoidal surgery; 5. Participated in clinical trials of other drugs within 30 days; 6. Other circumstances preclude participation in completing the intervention follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Periprocedural complications;Visual field examination;Thyroid function;Osmotic pressure and specific gravity of urine;Sex hormones;Adrenalotropic hormone;Cortisol;Growth hormone and insulin-like growth factor;The electrolyte;Clinical manifestation;Angle of the optic chiasm and length of pituitary stalk; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urine volume in 24 hours;Intracranial pressure; | — |
Countries
China
Contacts
Public ContactHui Yang/Min long
The Second Affiliated Hospital of Army Medical University
Outcome results
None listed