Effects of surface anesthesia with 1% tetracaine on vagal reflex in microlaryngeal surgery: a double-blind, randomized, and placebo-controlled study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200057077

Enrollment

Unknown

Registered

2022-02-27

Start date

2022-02-21

Completion date

Unknown

Last updated

2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laryngeal diseases

Interventions

Tetracaine group:Tetracaine

Control group:Normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. ASA I-II; 2. Patients aged 18-70 years old to undergo elective supported laryngoscopic laryngeal surgery in Beijing Tongren Hospital; 3. BMI between 18-30 Kg/m2; 4. Agreed to participate in this study and signed an informed consent form before surgery.

Exclusion criteria

Exclusion criteria: 1. Foreseeable difficult airway; 2. Allergy to ester local anesthetics; 3. Atrioventricular block of second-degree or higher.

Design outcomes

Primary

Measure	Time frame
Incidence of vagal reflex;	—

Secondary

Measure	Time frame
Blood pressure;Postoperative sore throat;Recovery profiles;Adverse reactions;	—

Countries

China

Contacts

Public ContactWang Guyan

Beijing Tongren Hospital, Capital Medical University

guyanwang2006@163.com+86 13910985139

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026