None listed
Conditions
Interventions
Group B:propofol+butorphanol 10µg/kg
Group BL:propofol+bupropion 10µg/kg+lidocaine 1.5mg/kg
Group S:propofol+saline
Sponsors
The First Affiliated Hospital of Ji'nan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years; 2. BMI 18-30 kg/m^2; 3. ASA classification: ?-?; 4. Patients undergoing gastroenteroscopy; 5. Patients or their family members should voluntarily participate in this clinical trial and sign informed consent if they have a full understanding of the purpose and significance of this trial.
Exclusion criteria
Exclusion criteria: 1. Patients with diabetes (random blood sugar >=11.1mmlol/L), hypertension (systolic blood pressure above 160mmHg) or hypotension (systolic blood pressure 2 times the upper limit of normal; Total bilirubin >1.5 times the upper limit of normal; 6. Abnormal renal function, serum creatinine (cr) and/or urea nitrogen (BUN) >1.5 times the upper limit of normal; Dialysis patients; 7. Nervous system dysfunction, mental illness or cognitive dysfunction; 8. Patients with a history of psychotropic and narcotic drug abuse; 9. Patients who are allergic to the drugs used in this study or fall within the contraindications of drugs; 10. Participate in clinical trials of other drugs within 3 months; 11. Other conditions in which the investigator determined that the patient was not suitable for the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| propofol consumption per minute; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;heart rate;SPO2;procedure time;induction time;awakening time;time to ambulate;incidence of bucking or coughing;incidence of body movement;incidence of injection pain; | — |
Countries
China
Contacts
Public ContactLi Yalan
Outcome results
None listed