Severe pneumonia
Conditions
Interventions
intervention group:conventional pathogen detection test+point of care molecular test
control group :conventional pathogen detection test
Sponsors
China-Japan Friend Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Duration of onset <=7 days; 3. Oxygen saturation <93% or oxygen partial pressure <60mmHg without oxygen inhalation, or oxygenation index.300mmHg under oxygen inhalation; 4. The patient met the diagnostic criteria for community-acquired pneumonia, hospital-acquired pneumonia or ventilator-associated pneumonia; Diagnostic criteria for community-acquired pneumonia: the diagnostic criteria of ''Chinese Adult Guidelines for Diagnosis and Treatment of Community-acquired Pneumonia (2016 Edition)'' were met; Diagnostic criteria for hospital-acquired pneumonia: Meet the diagnostic criteria of ''Guidelines for the Diagnosis and Treatment of hospital-acquired Pneumonia and Ventilator-associated Pneumonia in Chinese Adults (2018 Edition)''; 5. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant patients; 2. Patients enrolled in this study within 90 days; 3. Patients with active tuberculosis; 4. Immunosuppressed patients: (1) Neutrophil deficiency (peripheral blood neutrophil count =20mg/ day (or equivalent dose of other hormones) for more than 30 days at onset; (5) CD4 cell count of peripheral blood T cell subsets <200/mm^3 during HIV infection; (6) Complement deficiency and immunoglobulin deficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| De-escalation rate of anti-infective therapy; | — |
Countries
China
Contacts
Public ContactCao Bin
Outcome results
None listed