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A molecular model based on DetermaRx to predict the risk of postoperative recurrence of stage IB lung adenocarcinoma and the efficacy of adjuvant therapy

A molecular model based on DetermaRx to predict the risk of postoperative recurrence of stage IB lung adenocarcinoma and the efficacy of adjuvant therapy

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056997
Enrollment
Unknown
Registered
2022-02-25
Start date
2022-04-01
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stage IB lung adenocarcinoma

Interventions

DetermaRx molecular model prediction group:

Sponsors

Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with lung adenocarcinoma resected by R0; 2. Stage IB (eighth TNM stage); 3. Complete clinical data and follow-up information; 4. Age >= 18 years; 5. Pulmonary lobectomy plus systematic lymph node dissection; 6. FFPE samples required for testing are available.

Exclusion criteria

Exclusion criteria: 1. Received neoadjuvant therapy before surgery; Postoperative radiotherapy was performed; 2. Incomplete follow-up information and lost follow-up; 3. Patients who had cancer other than NSCLC within the five years prior to the initiation of treatment in this study. Carcinoma in situ of the cervix cured basal cell carcinoma, bladder epithelial neoplasms (including Ta and Tis) were excluded; 4. Sublobectomy (wedge resection, segmental resection), lymph node sampling; 5. Moderate to severe organ dysfunction except for tumor; 6. Other conditions considered unsuitable for inclusion by the researcher.

Design outcomes

Primary

MeasureTime frame
Progression-free survival time;

Countries

China

Contacts

Public ContactWenyong Zhou

Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China

dr.zhouwenyong@foxmail.com+86 15821673400

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026