Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with severe knee osteoarthritis are eligible for TKA and UKA surgery; 2. No cognitive dysfunction or psychiatric history before surgery; 3. Age < 80, no gender limitation; 4. Body weight < 100 kg; 5. ASA score was I-II; 6. Clearly understand and voluntarily participate in the study, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Preoperative consciousness disorder or inability to cooperate with the interviewer due to other reasons; 2. Abnormal coagulation function and severe ligament instability; 3. Those who have a history of narcotic drug dependence or drug abuse and are taking hormone or opioid treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numerical rating scale (NRS) score at 10 m after 24h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Type, dose and duration of analgesic drugs used 24 hours after surgery (conversion of morphine equivalent);postoperative nausea and vomiting; | — |
Countries
China
Contacts
Qilu Hospital of Shandong University