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Non targeted metabonomics study of heart failure based on UHPLC-QTOF/MS and the study on the pathogenesis of heart failure

Non targeted metabonomics study of heart failure based on UHPLC-QTOF/MS and the study on the pathogenesis of heart failure

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056971
Enrollment
Unknown
Registered
2022-02-25
Start date
2022-03-05
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure

Interventions

Group 1 :

Sponsors

Shanghai Tongren Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Older than 18 and younger than 90 years; 2. Patients with dyspnea, high jugular vein pressure, elevated NT proBNP or BNP (NT proBNP >= 125 pg/mL or BNP >= 35 pg/mL), abnormal cardiac ultrasound imaging findings were diagnosed as heart failure.

Exclusion criteria

Exclusion criteria: 1. Patients who cannot tolerate surgery; 2. Pregnant women or women preparing to become pregnant in the next two years; 3. Patients with life expectancy less than 2 years; 4. Severe hepatic and renal insufficiency (ALT > 5 times ula, EGFR < 15mL/min/1.73mm2); 5. Known active malignant tumor diseases; 6. Patients considered unsuitable by the investigator to participate in this study.

Design outcomes

Primary

MeasureTime frame
small molecule metabolite;

Countries

China

Contacts

Public ContactSong Lei

Shanghai Tongren Hospital

848015859@qq.com+86 18817314732

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026