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Efficacy of serratus anterior plane nerve block and opioid for rescue analgesia after video-assisted thoracic surgery: a randomized controlled trial

Efficacy of serratus anterior plane nerve block and opioid for rescue analgesia after video-assisted thoracic surgery: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056962
Enrollment
Unknown
Registered
2022-02-24
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

video-assisted thoracic surgery

Interventions

Experimental group:Ultrasonic-guided serratus anterior plane block (0.33% of ropivacaine, 30 mL) was performed on the first postoperative day in group SB when patient NRS pain score at coughing >= 4.
Control group:Intravenous sufentanil 0.1 ug/kg will be administered on the first postoperative day in group SB when patient NRS pain score at coughing >= 4.

Sponsors

Department of Anesthesiology and Perioperative Medicine, Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with pain after video-assisted thoracic surgery and NRS score >= 4; 2. Unlimited gender, age >= 18 years; 3. Those who voluntarily join and sign informed consent after fully explaining the contents of the clinical trial.

Exclusion criteria

Exclusion criteria: 1. Patients in coma or unsound mind before operation; 2. Patients with ASA grade IV or V; 3. Patients with body mass index > 30 kg/m2; 4. Patients with hemodynamic instability; 5. Patients who have recently taken analgesic and sedative drugs; 6. Patients with previous disease-related pain; 7. Patients with a past history of opioid abuse; 8. Patients who are allergic to opioids or local anesthetics; 9. Patients with coagulation dysfunction; 10. Patients with infection or tumor at the puncture point of nerve block; 11. Pregnant or lactating patients; 12. Patients who have participated in other treatment in the last 6 months (when consent is obtained); 13. Patients judged to lack the ability of consent; 14. Other patients who are judged as inappropriate by the clinical responsible doctor or the clinical doctor in charge.

Design outcomes

Primary

MeasureTime frame
change of pain numerical rating scale (NRS) ;

Secondary

MeasureTime frame
duration of surgery;duration of anesthesia ;Interval between first block and second block;blood pressure;heart rate;Pulse Oxygen Saturation;Arterial blood gas;numerical rating scale (NRS) scores of rest pain;numerical rating scale (NRS) scores of cough pain;the Richmond Agitation-Sedation Scale (RASS) score;the effective compression of patient controlled intravenous analgesia (PCIA);Sufentanil dosage;postoperative nausea and vomiting;first postoperative ambulation time;chest tube extraction time;postoperative hospital-stay time;numerical rating scale (NRS) scores of rest pain;numerical rating scale (NRS) scores of cough pain;Incidence of postoperative pulmonary complications;first time of patient-controlled intravenous analgesia;first flatus after surgery;

Countries

China

Contacts

Public ContactYun Wu

Department of Anesthesiology and Perioperative Medicine, Second Affiliated Hospital of Anhui Medical University

wuyunanyi@163.com+86 13865958254

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026