An integrated multi-omics approach characterize the influence and mechanism of lung transplant recipient's airway microbiome on graft dysfunction

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200056908

Enrollment

Unknown

Registered

2022-02-22

Start date

2020-10-12

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung transplantation

Interventions

Test group:None

Control group:None

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Adults (age =18 years old); 2.Patients undergoing single-lung, double-lung or combined heart-lung transplantation.

Exclusion criteria

Exclusion criteria: 1.The survival time after lung transplantation or combined heart lung transplantation is = 3 days; 2.Poor compliance, unwilling to cooperate with researchers.

Design outcomes

Primary

Measure	Time frame
Flora species;Host transcriptome;Metabolomics;CCL1?CCL11?CCL24;IL-1?IL-2? IL-3?IL-4?IL-6?IL-7?IL-8;IL-10?IL-11?IL-12?IL-13?IL-17;	—

Secondary

Measure	Time frame
Forced expiratory volume in one second, FEV1;forced vital capacity, FVC;diffusing capacity of the lungs for carbon monoxide, DLCO;	—

Countries

China

Contacts

Public ContactJu Chunrong

First Affiliated Hospitol of Guangzhou Medical University

fyzscitgzy@yeah.net+86 15915761346

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026