Schizophrenia
Conditions
Interventions
Control group:Aripiprazole oral tablet
Experimental group:Aripiprazole orally disintegrating tablet
Sponsors
Huizhou Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients with schizophrenia (18 years old <60 years old), no gender limit; 2. Meet the ICD-10 F20 diagnostic criteria for schizophrenia; 3. Aripiprazole is to be prescribed (single drug or combined with other drugs); 4. The patient or legal guardian should fully understand the treatment and agree to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Had dental cleaning, oral surgery, orthodontic and other operations in the past 3 months; 2. Use antibiotics orally or orally within the past 1 month; 3. Used aripiprazole in the past 3 months; 4. Combined with serious oral diseases: such as severe congenital oral malformations, oral cancer, etc.; 5. Severe or unstable immune or inflammatory diseases; 6. Unable to cooperate with oral sample sampling; 7. Failure to follow the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral health scale;Oral microbiome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical indicators of oral health;Positive and negative symptom scales; | — |
Countries
China
Contacts
Public ContactHuang Huawei
Huizhou Second People's Hospital
Outcome results
None listed