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Study on pathogenesis of NONFH and screening of diagnostic markers

Study on pathogenesis of NONFH and screening of diagnostic markers

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056864
Enrollment
Unknown
Registered
2022-02-21
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

femoral head necrosis

Interventions

Gold Standard:Clinical outcomes
Index test:1. Marker research this experiment can select blood samples from normal patients and disease patients, extract blood exosomes by SEC method, explore the protein changes of blood exosomes in
Or take blo

Sponsors

The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Meeting the diagnostic criteria of osteonecrosis of the femoral head in Adults Expert Consensus on Diagnosis and treatment Standards of osteonecrosis of the femoral head (2012 edition); 2. Patients aged >=18 years with informed consent; 3. No long-term use of other drugs affecting bone metabolism, no history of hip trauma.

Exclusion criteria

Exclusion criteria: Patients with mental illness, clinically unable to cooperate.

Design outcomes

Primary

MeasureTime frame
Exosome of blood;Protein marker;—

Countries

China

Contacts

Public ContactXu Xilin

The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine

eastoph@sina.com+86 15504579627

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026