acute gastrointestinal injury (AGI)
Conditions
Interventions
short peptide group:Short peptide feeding regimen
whole protein group:Whole protein feeding program
Sponsors
First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged >18 years. 2. Admission to ICU meets the 2012 ESICM criteria for acute gastrointestinal injury grade I (risk of gastrointestinal dysfunction and failure) and AGI grade II (gastrointestinal dysfunction), and enteral nutrition can be initiated within 24 to 48 hours.
Exclusion criteria
Exclusion criteria: 1. There are contraindications of enteral feeding and hemodynamic instability, which cannot be given any form of nutritional treatment; 2. Patients with oral feeding, chronic liver disease history and severe liver function damage during the course of the disease; 3. Serum urea nitrogen increased more than 4mmol/L daily, or renal insufficiency required blood purification treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| D lactic acid;diamine oxidase;endotoxin;quadriceps muscle thickness;rectus femoris cross-sectional area;biceps brachii thickness;prealbumin;ICU mortality;90 day mortality;acute gastrointestinal injury classification; | — |
Countries
China
Contacts
Public ContactZhang Dong
The First Hospital of Jilin University
Outcome results
None listed