Senile cataract, acute angle closure, anterior angle morphology
Conditions
Interventions
Observation group:UBM quantitative parameters of anterior chamber angle were measured in sitting position and decubitus position
Sponsors
The Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. No major basic medical or surgical diseases. (For hypertensive patients, the mean blood pressure (BP) measured at admission, before surgery and three times after surgery was not more than 150mmHg for systolic blood pressure and 100mmHg for diastolic blood pressure. Diabetic patients: preoperative fasting blood glucose less than 8mmol/L. Patients with renal failure dialysis, immune diseases requiring long-term oral steroids, and long-term chemotherapy after malignant tumor surgery were excluded). 2. Onset of monocular acute angle-closure glaucoma, onset of disease less than 5 days. Both eyes did not receive medication, laser and surgical intervention (including anterior chamber puncture) before admission. History of ocular trauma was denied in both eyes. 3. Ophthalmic examination (including slit-lamp, anterior chamber angle lens, 90D front lens, UBM, A-Scan) did not find iris root detachment, anterior chamber angle retreat, and anterior and posterior segment occupation (solid mass such as choroid, ciliary body melanoma, or metallic/nonmetallic foreign body, cystic mass such as ciliary body, iris cyst, etc.), suprachoroidal effusion (ciliary body or choroid detachment), retinal detachment, acute or old uveal inflammation and other ophthalmic diseases affecting the atrial angle status. 4. The typical features of acute angle closure crisis (AACC) at the onset of disease are as follows: (1) A history of at least one of the following symptoms: periocular pain, headache, nausea with/or vomiting, vision loss, with/or intermittent iridosis; (2) Intraocular pressure (IOP) >= 21 mmHg (measured by Goldmann tonometer); (3) The trabecular contact range of the chamber Angle was observed to be more than 180 degree; (4) At least the following four ocular signs were observed under slit-lamp: ciliary congestion, corneal endothelial edema, fixed medium size pupil, glaucoma spot, and peripheral anterior chamber shallow. 5. The clinical characteristics of the enrolled cases (case group) suggested the possibility of lens derived acute atrial angle closure (lens swelling, anterior iris septum, lens shaking, iris tremor, etc.), mild or above lens opacification, and a strong desire to improve visual function. 6. All enrolled cases (case group) underwent cataract lens extraction. Extracapsular lens extraction (ECCE), phacoemulsification (Phaco) and posterior approach lens resection (Vitrectomy) were selected according to preoperative examination and intraoperative conditions. Intraoperative procedures may include external trabeculectomy, simple periiridotomy, anterior chamber Angle separation, intraocular lens implantation, or posterior vitrectomy. 7. The enrolled cases (control group) were all eyes with simple senile cortical cataract (without the symptoms and signs of lens dislocation and acute angle closure).
Exclusion criteria
Exclusion criteria: 1. Allergic to mydriatic drugs (compound tropinamide eye drops: 0.5% tropicamide mixed with 0.5% hydrochloric acid desoxyadrenaline) and topical anesthesia drugs (orbucaine hydrochloride eye drops: 0.4% orbucaine solution, 20ml:80mg). 2. Cases with poor image resolution in imaging examinations such as UBM and A-Scan, and unable to clearly distinguish anatomical structure and morphological features. 3. Cases with incomplete clinical data that cannot be analyzed in the later stage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anterior chamber depth;The lens arches high;The opening distance of the chamber angle;Trabecular iris angle;Angle between the lens and the iris; | — |
Countries
China
Contacts
Public ContactWang Fenglei
The Affiliated Hospital of Qingdao University
Outcome results
None listed