Cerebral vascular disease
Conditions
Interventions
Experimental group:The pathophysiology was evaluated by 3D-ASL-DWI and DWI-FIAIR double mismatch technique + rt-PA intravenous thrombolysis and endovascular treatment
Control group:rt-PA intravenous thrombolysis and endovascular treatment
Sponsors
Aerospace Center Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 88 Years
Inclusion criteria
Inclusion criteria: 1. Patients with anterior circulation acute cerebral infarction at an uncertain time of onset, including stroke after awakening. 2. The time to admission was less than 3.5 hours after being found to have stroke-like symptoms. 3. Aged >=18 years.
Exclusion criteria
Exclusion criteria: 1. Significant head trauma or stroke in the last 3 months. 2. Symptoms suggestive of subarachnoid hemorrhage. 3. Puncture of an artery at an incompressible site within the last 7 days. 4. History of intracranial hemorrhage. 5. Intracranial tumors, arteriovenous malformations, and aneurysms (unbroken aneurysms 185mmHg or diastolic blood pressure > 110mmHg). 8. Active internal bleeding. 9. Acute bleeding diathesis, including but not limited to a platelet count 40S) in the last 48 hours of heparin therapy. 11. Taking an oral anticoagulant: INR > 1.7 or PT > 15 seconds. 12. A direct thrombin inhibitor or a direct factor ?a inhibitor is being used, and sensitive laboratory measures (e.g., aPTT, INR, platelet count, and venomase clotting time (ECT), thrombin time (TT), or factor ?a measurement as appropriate) are elevated. 13. Blood glucose concentration 1/3 of the cerebral hemisphere).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale (mRS) Score;National Institutes of Health Neurological Deficit Score (NIHSS); | — |
Countries
China
Contacts
Public ContactWang Peifu
Aerospace Center Hospital
Outcome results
None listed