healthy
Conditions
Interventions
Group A:The first stage intervention dose: 500mg, the second stage intervention dose: 1000mg, and the third stage intervention dose:2000mg
Group B:The first stage intervention dose: 1000mg, the second stage intervention dose: 2000mg, and the third stage intervention dose: 500mg
Group C:The first stage intervention dose: 2000mg, the second stage intervention dose: 500mg, and the third stage intervention dose: 1000mg
Sponsors
Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Healthy adult volunteers who meet the recruitment conditions are included: 1. Older than 18 years old; 2. According to the evaluation of disease history, blood biochemistry, blood routine and other modules, they were normal
Exclusion criteria
Exclusion criteria: Main exclusion criteria: 1. Cold and fever; 2. Recent drug intake (including dietary supplement intake); 3. Alcohol intake; 4. BMI 30kg / m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nicotinamide adenine dinucleotide; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hydroxymethylnicotinamide;N-methyl-2-pyridone- 5-carboxamide;N-methyl-4-pyridone-3- carboxamide;nicotinamide riboside;ß-nicotinamide mononucleotide;nicotinamide;nicotinamide adenine dinucleotide phosphate; | — |
Countries
China
Contacts
Public ContactLi Songtao
Outcome results
None listed