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Effect of single oral administration of ß-nicotinamide mononucleotide(NMN) on the content of nicotinamide adenine dinucleotide (NAD+) in healthy men

Effect of single oral administration of ß-nicotinamide mononucleotide(NMN) on the content of nicotinamide adenine dinucleotide (NAD+) in healthy men

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056797
Enrollment
Unknown
Registered
2022-02-17
Start date
2022-06-08
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy

Interventions

Group A:The first stage intervention dose: 500mg, the second stage intervention dose: 1000mg, and the third stage intervention dose:2000mg
Group B:The first stage intervention dose: 1000mg, the second stage intervention dose: 2000mg, and the third stage intervention dose: 500mg
Group C:The first stage intervention dose: 2000mg, the second stage intervention dose: 500mg, and the third stage intervention dose: 1000mg

Sponsors

Zhejiang Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Healthy adult volunteers who meet the recruitment conditions are included: 1. Older than 18 years old; 2. According to the evaluation of disease history, blood biochemistry, blood routine and other modules, they were normal

Exclusion criteria

Exclusion criteria: Main exclusion criteria: 1. Cold and fever; 2. Recent drug intake (including dietary supplement intake); 3. Alcohol intake; 4. BMI 30kg / m2

Design outcomes

Primary

MeasureTime frame
nicotinamide adenine dinucleotide;

Secondary

MeasureTime frame
Hydroxymethylnicotinamide;N-methyl-2-pyridone- 5-carboxamide;N-methyl-4-pyridone-3- carboxamide;nicotinamide riboside;ß-nicotinamide mononucleotide;nicotinamide;nicotinamide adenine dinucleotide phosphate;

Countries

China

Contacts

Public ContactLi Songtao
lisongtao@zcmu.edu.cn18989487582

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026