Prima angle closure disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Voluntarily sign the informed consent of this study 2. Chinese male or female patients aged 18-80 years, including 18 and 80 years. Primary Angle-closure Glaucoma suspect (PACS) and primary Angle-closure glaucoma suspect (PACS). Clinical diagnosis of primary Angle-closure glaucoma (PACG): (1) Primary angle closure suspect: difficult to see pigment trabecular meshwork (i.e. contact of iris trabecular meshwork) by anterior chamber angle, and the IOP was 180, (or) there was adhesion of peripheral anterior chamber Angle, no glaucoma optic nerve injury, accompanied by intraocular pressure >=22mmHg; (3) PACG: meet the diagnostic conditions of PAC and have glaucomatous optic neuropathy or glaucomatous visual field defect; 4. With or without cataracts.
Exclusion criteria
Exclusion criteria: 1. Acute primary angle-closure (APAC) or ACUTE onset of PACG; 2. Unable or unwilling to sign a consent form, unable to follow study procedures, and unable to cooperate with eye examinations; 3. Secondary angle-closure glaucoma: lens dislocation, uveitis, trauma, and neovascular glaucoma; 4. Those who have had previous surgery or are expected to have other surgery: had previously undergone damaging ciliary body surgery, cataract surgery with or without IOL implantation; No lens eye; Additional eye surgery or other eye operations are expected; 5. Associated with other diseases or abnormalities of the eye, including corneal abnormalities or corneal infection; iridocorneal endothelial syndrome, anterior segment hypoplasia, nanophthalmos, high myopia (>6.0D), uveitis, ocular tumor, ocular trauma, fundus lesions such as central retinal vein obstruction, central retinal artery obstruction, retinal detachment, etc.; 6. Pregnant or Breast Feeding women or whom with a history of serious systemic diseases: diabetes, hypertension (systolic blood pressure >=180mmHg or diastolic blood pressure >=100mmHg), advanced heart disease, kidney disease, respiratory disease or tumor, etc.; 7. Patients with autoimmune diseases require long-term use of local and systemic hormones or the presence of hormone therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasound biomicroscopy;Anterior segment optical coherence tomography;Swept source optical coherence tomography;AB-mode diagnostic ultrasonic apparatus; | — |
Countries
China
Contacts
Beijing Tongren Hospital, Capital Medical University