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Study of heparin regulating PTN/syndecan-3 in cerebral injury and repair mechanism after cardiopulmonary resuscitation

Study of heparin regulating PTN/syndecan-3 in cerebral injury and repair mechanism after cardiopulmonary resuscitation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056736
Enrollment
Unknown
Registered
2022-02-12
Start date
2022-02-01
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac arrest

Interventions

None listed

Sponsors

Ningxia Hui Autonomous Region People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age > 18 years; 2. Diagnostic criteria of cardiac arrest and recovery of spontaneous circulation; 3. Less than 24 hours from onset to admission; 4. Provide and sign written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with obvious liver, kidney, and heart failure; 2. Complicated with diseases of the blood system, tumors of the central nervous system or spinal column, systemic malignancy, etc.; 3. Complicated with metabolic diseases or receiving hormone and immunosuppressive therapy; 4. With demyelinating disease, Parkinson's disease, dementia, and other neurological diseases; 5. Have a history of stroke or sequelae of stroke within 1 year; 6. Previous spinal or craniocerebral surgery or major surgery or trauma within 1 month.

Design outcomes

Primary

MeasureTime frame
PTN;SDC3;—

Secondary

MeasureTime frame
Glasgow Coma Scale, GCS;Telephone Interview for Cognitive Status-Modified, TICS-m;—

Countries

China

Contacts

Public ContactYe Qingshan

Ningxia Hui Autonomous Region People's Hospital

yeqingshan@hotmail.com+86 17395055188

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026