Clinical application of plateau pressure-limited low tidal volume mechanical ventilation after positive end-expiratory pressure and its effect on postoperative pulmonary complications

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200056720

Enrollment

Unknown

Registered

2022-02-11

Start date

2022-02-07

Completion date

Unknown

Last updated

2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical ventilation patient

Interventions

LPV group:Lung protective ventilation

Control group:No lung protective ventilation

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. American Society of anesthesiologists health status rating (ASA) 1-2; 2. Aged between 18 and 75 years old; 3. Patients undergoing elective abdominal surgery under general anesthesia for more than 2 hours.

Exclusion criteria

Exclusion criteria: 1. Those who refuse to participate in the experiment and do not sign the informed consent form; 2. Patients with serious heart, kidney, or liver diseases, chronic obstructive pulmonary disease, chest wall deformity, or a history of chest surgery; 3. Body mass index (BMI) 30kg/m2; 4. Patients had symptoms of upper respiratory tract infection or pulmonary infection in recent 4 weeks, and chest X-ray or CT showed pneumonia.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative pulmonary complications;	—

Countries

China

Contacts

Public ContactDong Chunshan

The Third Affiliated Hospital of Anhui Medical University (Hefei First People's Hospital)

cxh0909@vip.126.com+86 15805604825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026