The efficacy and safety of regulating autonomic nerve function by non-invasive peripheral compression training in the treatment of refractory epilepsy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200056711

Enrollment

Unknown

Registered

2022-02-11

Start date

2022-02-10

Completion date

Unknown

Last updated

2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Interventions

Experimental group:Noninvasive peripheral compression

Eligibility

Sex/Gender

All

Age

14 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Age 14-65 years old; 2. Diagnosed as refractory epilepsy.(resistant to AED medication for at least 2 years); 3. Agree to participate in this study and signed on the informed consent.

Exclusion criteria

Exclusion criteria: 1. With brain tumor or other central nervous system degenerative diseases; 2. With intracranial aneurysm, arteriovenous malformation or MoyaMoya syndrome; 3. Pregnant or those with high risk of hemorrhage; 4. Systolic blood pressure > 160 mmHg; 5. Other factors that researchers considered it unsuitable for inclusion.

Design outcomes

Primary

Measure	Time frame
The frequency and severity of seizures;	—

Secondary

Measure	Time frame
The patient’s quality of life (QOLIE-31 scale);Cognitive scale (MMSE scale);The score of Anxiety scale (GAD-7) and depression scale (NDDI-E);The score of Sleep quality scale (PSQI scale);	—

Countries

China

Contacts

Public ContactLiankun Ren

Xuanwu Hospital, Capital Medical University

rlkbrain2000@yahoo.com+86 13681576621

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026